Methionine enkephalin inhibits the bursting activity of the Br-type neuron inHelix pomatia L. |
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| Authors: | G B Stefano I Vadasz L Hiripi |
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| Institution: | (1) Biological Research Institute of the Hungarian Academy of Sciences, Tihany, (Hungary);(2) Department of Natural Sciences, Medgar Evers College of Cuny, 11225 Brooklyn, N.Y., USA;(3) Present address: East Coast Neuroscience Foundation Inc., 113 Bayview Ave., 11768 Northport, N.Y., USA |
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| Abstract: | Summary The present study demonstrates that methionine enkephalin can inhibit the normal bursting activity pattern of the RPal or Br-type neuron and this inhibition can be blocked by prior treatment with naloxone, the selective opiate antagonist. The study demonstrates indirectly the presence of opiate-like receptors inHelix pomatia.Acknowledgments. This work was funded by grant RR 08171 Division of Research Resources and NIMH, and a National Academy of Sciences Travel grant and a Hungarian Academy of Sciences research support award to G.B.S. We also gratefully acknowledge thoughtful comments from Dr J. Salanki. |
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