Subpopulations of T-lymphocytes in Peyer's patches: Sensitivity to antilymphocyte serum and adult thymectomy |
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Authors: | D. Vuitton R. Eloy F. Gosse A. Pousse J. F. Grenier |
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Affiliation: | (1) Unité 61 INSERM, Unit of Surgical Research and Biophysiopathology of the Intestine, Avenue Molière, F-67200 Strasbourg-Hautepierre, (France) |
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Abstract: | Summary Anti-lymphocyte (ALS) treatment or adult thymectomy of the donor have been shown to depress respectively the cell proliferation and the cytotoxicity in the graft-versus-host (GVH) reaction. A quantitative assay and the histological criteria of the GVH reaction have been used to demonstrate that all the known subpopulations of T-lymphocytes involved in the GVH reaction are present in the Peyer's patches as well as in the spleen and mesenteric lymph nodes in the rat.This work was supported by a grant of the Délégation Générale à la Recherche Scientifique et Technique (No. 74-7-0619). |
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