瑶药少花海桐茎皮挥发油化学成分研究

【目的】分析鉴定瑶药少花海桐(Pittosporum pauciflorum)茎皮中挥发油的主要化学成分,为其质量控制及其挥发油的开发利用提供依据。【方法】采用水蒸气蒸馏法提取少花海桐茎皮中的挥发油,运用GC-MS对其化学成分进行分析鉴定,并用面积归一化法从总离子流图中计算各组分的峰面积相对百分比。【结果】少花海桐茎皮中挥发油含量约为0.09%;从茎皮中共分离并鉴定出29个化合物,主要为月桂醇酯(41.82%)、月桂醛(12.8%)、肉豆蔻醛(14.64%)、豆蔻醇(13.5%)、乙酸十四酯(4.54%)、十一烷(4.21%)等酯类、醛类、醇类、烷烃类及烯烃类化合物;已鉴定成分峰面积达色谱总馏出峰面积的97.5%。【结论】本研究可为瑶药少花海桐药材及制剂的质量控制及其挥发油的综合开发利用提供研究基础与科学依据。

Study on the Chemical Constituents of Volatile Oil from Bark of Pittosporum pauciflorum

Objective] Analyzing and identifying the chemical constituents of the volatile oil from bark of Pittosporum pauciflorum to provide basis for its quality control and the development and utilization of volatile oil.Methods] The volatile oil was extracted by hydrodistillation and the chemical components were analyzed by GC-MS,and the relative percentage of the peak area was calculated from the total ion flow chart by the area normalization method.Results] The volatile oil content of bark of Pittosporum pauciflorum was about 0.09%,and 29 compounds were isolated and identified from the bark,their peak areas accounted for 97.5% of the total. They were mainly esters,aldehydes,alcohols and alkanes,such as lauryl acetate(41.82%),dodecanal(12.8%),tetradecanal(14.64%),1-tetradecanol (13.5%),tetradecyl acetate(4.54%) and undecane(4.21%).Conclusion] The study can provide foundation and scientific basis for the quality control of Pittosporum pauciflorum and the development and utilization of volatile oil.