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Evidence for a selective cytotoxic effect of carrageenan on cells of the immune system in vivo and in vitro |
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| Authors: | A. W. Thomson A. R. Wilson W. J. Cruickshank Audrey H. Jeffries |
| Affiliation: | (1) Department of Zoology, University of Aberdeen, AB9 2TN Aberdeen, (Scotland);(2) Present address: Department of Pathology, University Medical Buildings, Foresterhill, AB9 2ZD Aberdeen, Scotland |
| Abstract: | Summary Carrageenan suppressed antibody production to sheep erythrocytes in the mouse only when injected together with or 24 h prior to antigen. Pretreatment of sensitized spleen cell cultures with carrageenan reduced the degree of stimulation obtained using antigen but not PHA. |
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