Evidence that the prostaglandin-like substances fromPropionibacterium acnes are not identical with PGE2 |
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| Authors: | S Abrahamsson K Gréen L Hellgren J Vincent |
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| Institution: | (1) Department of Structural Chemistry, Faculty of Medicine, University of Göteborg, Göteborg;(2) Department of Chemistry, Karolinska Institutet, Stockholm, Sweden;(3) Department of Dermatology, University of Trondheim, Trondheim, Norway |
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| Abstract: | Summary The prostaglandin-like substances (PLS) isolated fromP. acnes were investigated by reversed phase chromatography and gas chromatography-mass spectrometry. These analyses demonstrated that PLS were not identical with PGE2, which supports a concept of PLS as a potential mediator of the inflammatory process in acne vulgaris. |
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