Changes in the concentration of vasoactive intestinal peptide in intestinal lymph in response to vagal stimulation in the calf |
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| Authors: | A V Edwards P M M Bircham S J Mitchell S R Bloom |
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| Institution: | (1) Physiological Laboratory, Downing Street, CB2 3EG Cambridge, (England);(2) Department of Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, W12 London, (England) |
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| Abstract: | Summary Stimulation of both vagi caused a significant rise in arterial plasma vasoactive intestinal peptide (VIP) concentration in 3–5-week-old calves with cut splanchnic nerves. This was associated with a pronounced rise in the VIP concentration of intestinal lymph showing that vagal stimulation causes release of VIP from splanchnic viscera.Acknowledgment. This work has been supported by grants from the Agricultural Research Council and the Medical Research Council and we are indebted to Dr D.M. Burley (CIBA) for his continued support. |
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