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IgM类HBsAg免疫复合物与乙肝肝损害关系初探
引用本文:李思光,彭宣宪.IgM类HBsAg免疫复合物与乙肝肝损害关系初探[J].江西科学,1997,15(3):154-157.
作者姓名:李思光  彭宣宪
作者单位:南昌大学生物科学工程系!南昌,330047,厦门大学肿瘤细胞工程国家专业实验室!厦门,361005,南昌大学生物科学工程系!南昌,330047,南昌大学生物科学工程系!南昌,330047
摘    要:对六类不同临床病型236例乙3肝患者的IgM类HBsAg循环免疫复合物(HBsAg/IgM-CIC)阳性率与ALT和肝损害严重性之间的相互关系进行了探讨。结果发现,其阳性率与肝损害严重程度呈正相关,与ALT的关系则取决于临床类型。提示免疫复合物的肝损作用具有临床类型相关性的异质性。

关 键 词:乙型肝炎  循环免疫复合物  肝损害

RELATIONSHIPS BETWEEN HBsAg/IgM-CIC AND DEGREE OF LIVER DAMAGE IN PATIENTS WITH HEPATITIS B VIRUS INFECTIONS
Li siguang,Peng Xuanxian, Zhang Wenjun,Zhou Yulin.RELATIONSHIPS BETWEEN HBsAg/IgM-CIC AND DEGREE OF LIVER DAMAGE IN PATIENTS WITH HEPATITIS B VIRUS INFECTIONS[J].Jiangxi Science,1997,15(3):154-157.
Authors:Li siguang  Peng Xuanxian  Zhang Wenjun  Zhou Yulin
Abstract:The relationships between HBsAg/IgM circulating immune complexes (HBsAg/IgM -CIC)and ALT level and the degree of liver damage were studied in patients infected with hepatitis B virus. It was found that the positive rates of the complexes were positively correlated with the degree of liver damage and ALT level in different clinical types of hepatitis B virus infection. These findings suggested that the two factors of clinical types and immunoglobulin classes are involved in the function of liver damage of immune complexes.
Keywords:Hepatitis B  Circulating immune complexes  Liver damage  HBsAg  IgM
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