Zentralerregende Wirkung eines neuen Piperidinderivates

Summary A new piperidine derivative, the 2-diphenylmethylpiperidine, produces already in doses of 0.001 g/kg s.c. a strong increase of the spontaneous motility of various animals. On mice it has about the same potency as d-desoxy-ephedrine and is about 3 times more potent than amphetamin. It also acts markedly antagonistic on various narcotics but has practically no peripheral sympathomimetic effects.

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8. Mitteilung über Alkylenimin-Derivate. 7. Mitteilung sieheB. M. Iselin undK. Hoffmann, J. Am. Chem. Soc.76 (im Druck).