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Effects of altered thyroid state on the inhibition produced by locus coeruleus in purkinje cells in the rat
Authors:Dolores Fuenmayor  J. A. Gonzalez-Vegas
Affiliation:(1) Escuela de Bioanalisis, Facultad de Medicina, Universidad Central, Caracas, (Venezuela)
Abstract:Summary The number of cerebellar Purkinje cells inhibited after locus coeruleus stimulation was found to be greater in hyperthyroid rats than in control healthy animals; these in turn showed a higher percentage of inhibited cells than hypothyroid rats. It is concluded that thyroid hormone is capable of modulating synaptic activity in the LC-PC pathway.
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