Constituents ofCannabis sativa L. XXI: Estrogenic activity of a non-cannabinoid constituent |
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Authors: | Ph. W. Wirth J. C. Murphy F. S. El-Feraly C. E. Turner |
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Affiliation: | (1) Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, 38677 University, Miss., USA |
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Abstract: | Summary A non-cannabinoid phenol (4,4,dihydroxy-5-methoxybibenzyl) increased uterine weight in prepubescent female rats, suggesting non-cannabinoids contribute to the estrogenic effects ofCannabis.Acknowledgments. This research was supported by Contract 271-78-3527 from the National Institute on Drug Abuse and by the Research Institute of Pharmaceutical Sciences, University of Mississippi. The authors are grateful to Karen S. Tomaszewski for technical assistance. |
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