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| 子宫内膜异位症大鼠子宫内膜白细胞介素-6 mRNA表达的变化 | |
| 引用本文： | 郑辉,王自能,曹佐武,廖继东,赵昕,马秀君. 子宫内膜异位症大鼠子宫内膜白细胞介素-6 mRNA表达的变化[J]. 暨南大学学报(自然科学与医学版), 2002, 23(2): 11-14 |
| 作者姓名： | 郑辉 王自能 曹佐武 廖继东 赵昕 马秀君 |
| 作者单位： | 1. 暨南大学医学院:生理教研室,广东,广州,510632 2. 暨南大学医学院:妇产科教研室,广东,广州,510632 3. 暨南大学医学院:生殖免疫中心,广东,广州,510632 4. 暨南大学医学院:中心实验室,广东,广州,510632 |
| 摘 要： | 目的：探讨大鼠子宫内膜异位症（内异症）发生、发展过程中子宫内膜白细胞介素－6（IL－6）mRNA表达的变化。方法：利用大鼠内异症动物模型，采用逆转录聚合酶链反应（RT－PCR）技术，检测子宫内膜白细胞介素－6（IL－6）mRNA表达情况。结果：正常对照组，各时间点间2、4、6和8周）IL－6mRNA表达无显著性差异（P＞0．05）。内异症模型组，在成模后2、4、6和8周其在位、异位子宫内膜IL－6mRNA的表达呈增高趋势（P＜0．01）。结论：IL－6mRNA可能与内异症的进展有关。 |
| 关 键 词： | 白细胞介素－6mRNA 子宫内膜异位症 大鼠 |
| 文章编号： | 1000-9965(2002)02-0011-04 |
| 修稿时间： | 2001-11-23 |
The expression of interleukin-6(IL-6) mRNA in experimentally induced endometriosis in rats |
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| ZHENG Hui ,WANG Zi-neng ,CAO Zuo-wu ,LIAO Ji-dong ,ZHAO Xin ,MA Xiu-jun. The expression of interleukin-6(IL-6) mRNA in experimentally induced endometriosis in rats[J]. Journal of Jinan University(Natural Science & Medicine Edition), 2002, 23(2): 11-14 | |
| Authors: | ZHENG Hui WANG Zi-neng CAO Zuo-wu LIAO Ji-dong ZHAO Xin MA Xiu-jun |
| Affiliation: | ZHENG Hui 1,WANG Zi-neng 2,CAO Zuo-wu 3,LIAO Ji-dong 4,ZHAO Xin 4,MA Xiu-jun 4 |
| Abstract: | Aim: The purpose of our study was to explore expression of interleukin-6(IL-6) mRNA in experimentally induced endometriosis in rat. Methods: The endometrium was examined by RT-PCR. Results: The expression of IL-6 mRNA in controls did not change at 2, 4, 6 and 8 weeks after sham operation (P>0.05) , but in models it gradually increased at 2, 4, 6 and 8 weeks after endometriosis (P<0.01). Conclusion: The IL-6 mRNA may be associate with the development of endometriosis. |
| Keywords: | interleukin-6 mRNA endometriosis rat |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |