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Latent iron deficiency alters gamma-aminobutyric acid and glutamate metabolism in rat brain
Authors:Dr. A. Shukla  K. N. Agarwal  G. S. Shukla
Affiliation:(1) Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, (India);(2) Neuroscience Laboratory Building, The University of Michigan, 48104 Ann Arbor, Michigan, USA;(3) Neuroscience Laboratory Building, The University of Michigan, 1103 East Huron, 48104-1687 Ann Arbor, MI, USA
Abstract:Summary A diet containing 18–20 mg iron/kg to young weaned rats for 8 weeks altered the metabolism of gamma-aminobutyric acid and glutamate in the central nervous system without affecting blood hemoglobin. Subsequent rehabilitation with 390 mg iron/kg diet for 2 weeks normalized these changes.
Keywords:Latent iron deficiency  brain  GABA  glutamate  enzymes  rehabilitation
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