Application of image alignment and time averaging methods in AFM detection for single DNA molecules |
| |
Authors: | ChunMei Wang JieLin Sun Fei Long Jun Zhao Jun Hu |
| |
Affiliation: | 1 School of Life Science and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China; 2 Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China |
| |
Abstract: | Enhancement of the SNR (signal to noise ratio) in single-molecule imaging is significantly important for improving image resolu-tion and distinguishing the fine structures of single molecules at a higher precision level.Image processing techniques have dem-onstrated the remarkable capability to improve the SNR and the resolution level by breaking through some inherent limitations unresolved by instrument hardware optimization.In this paper, we focus on single-biomolecule imaging using atomic force mi-crosco... |
| |
Keywords: | image alignment DNA AFM time averaging SNR |
本文献已被 CNKI SpringerLink 等数据库收录! |
| 点击此处可从《科学通报(英文版)》浏览原始摘要信息 |
|
点击此处可从《科学通报(英文版)》下载全文 |