Comparing peripheral glial cell differentiation in <Emphasis Type="Italic">Drosophila</Emphasis> and vertebrates |
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Authors: | Floriano?Rodrigues Imke?Schmidt Email author" target="_blank">Christian?Kl?mbtEmail author |
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Institution: | 1.Institut für Neurobiologie,Münster,Germany |
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Abstract: | In all complex organisms, the peripheral nerves ensure the portage of information from the periphery to central computing
and back again. Axons are in part amazingly long and are accompanied by several different glial cell types. These peripheral
glial cells ensure electrical conductance, most likely nuture the long axon, and establish and maintain a barrier towards
extracellular body fluids. Recent work has revealed a surprisingly similar organization of peripheral nerves of vertebrates
and Drosophila. Thus, the genetic dissection of glial differentiation in Drosophila may also advance our understanding of basic principles underlying the development of peripheral nerves in vertebrates. |
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