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Effect of the type of diet on the distribution of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase in rat small intestine
Authors:M Sugano  Y Fujisaki
Institution:(1) Laboratory of Nutrition Chemistry, Kyushu University School of Agriculture, Higashi-ku, 812 Fukuoka, (Japan)
Abstract:Summary The jejunoileal gradient for the HMG-CoA reductase activity in the microsomal fraction of the epithelial cells of the small intestine of rats given commercial pellets was reserved within a few days after changing the ration to a semipurified diet. The response of the reductase was essentially the same in villus and crypt cells.
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