Effects of isoproterenol and dopamine on the myocardial hexose monophosphate shunt |
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| Authors: | H -G Zimmer H Ibel |
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| Institution: | (1) Physiologisches Institut der Universität, Pettenkoferstrasse 12, D-8000 München 2, (Federal Republic of Germany) |
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| Abstract: | Summary Long-term exposure of rats to isoproterenol and dopamine resulted in an increase of glucose-6-phosphate dehydrogenase activity and a greater availability of 5-phosphoribosyl-1-pyrophosphate in the myocardium. These results are interpreted to indicate an enhanced flow through the hexose monophosphate shunt.Supported by the Deutsche Forschungsgemeinschaft (Zi 199/1). The excellent technical assistance of Miss G. Steinkopff is gratefully acknowledged. |
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