| 强啡肽(DYN)对人胎盘绒毛组织促性腺素分泌的影响 |
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| 引用本文： | 张涛,王红,张崇理,王龙. 强啡肽(DYN)对人胎盘绒毛组织促性腺素分泌的影响[J]. 山东大学学报(理学版), 1991, 0(1) |
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| 作者姓名： | 张涛 王红 张崇理 王龙 |
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| 作者单位： | 山东大学生物系，中国科学院动物研究所，中国科学院动物研究所，山东大学生物系 |
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| 摘 要： | 用胎盘绒毛组织体外孵育法(无血清培液)研究了强啡肽对妊娠6～10周人胎盘绒毛组织分泌促性腺素的影响.结果表明,当DYN浓度为10~(-9)mol/L,与对照组相比,有明显的刺激作用(P<0.05);浓度为10~(-10)mol/L,刺激作用最强(p<0.001).DYN可能在胎盘绒毛组织分泌hCG中起重要作用.
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| 关 键 词： | 人早期胎盘绒毛组织 组织培养 强啡肽 绒毛膜促性腺素 放射免疫测定 |
EFFECT OF DYN ON hCG RELEASE FROM HUMAN PLACENTA VILLI OF EARLY PREGNANCY (6-10 WEEKS) |
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| Zhang Tao, Wang Long. EFFECT OF DYN ON hCG RELEASE FROM HUMAN PLACENTA VILLI OF EARLY PREGNANCY (6-10 WEEKS)[J]. Journal of Shandong University, 1991, 0(1) |
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| Authors: | Zhang Tao Wang Long |
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| Affiliation: | Zhang Tao, Wang Long Department of Biology,Shandong University,JinanWang Hong, Zhang Chongli Department of Endocrinology and Laboratory of Reproductive Biology,Institute of Zoology,Academia Sinica,Beijing |
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| Abstract: | The effect of DYN on hCG release from human placenta villi of early pregnancy (6-10 weeks) was studied in vitro. Placenta villi were incubated in serum-free McCoy's 5a medium. The results show that DYN stimulated hCG release from placenta villi. The hCG secretion increased and reached a maximum level at a dose of 10~(-10)mol/L (p<0.001), the dose of 10~(-9)mol/L also had a significant stimulating effect (p<0.05), but higher concentration of DYN could not augment hCG release markedly. It's concluded that DYN may play an important role in regulating hCG release. |
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| Keywords: | human placenta villi of early pregnancy tissue culture DYN hCG RIA |
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