The effect of age on cardiac output and its distribution in the rat

Summary Cardiac output distribution in the rat was found to be affected by age. Cardiac index and blood flow to the liver, kidneys, skin and skeletal muscle were lower in 11–12 month compared to 3–4 month old rats.Acknowledgments. This work was supported by grants from I.C.I. Pharmaceuticals and Mersey Regional Health Authority (Research Scheme No.338). We wish to thank Mr P.J. Roberts for invaluable technical assistance.