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The effect of combined chronic hypoxia and N-ethyl-N-nitrosourea on the carotid bodies of rats
Authors:P Laidler  J M Kay
Institution:(1) Department of Pathology, University of Liverpool, P.O. Box 147, L69 3 BX Liverpool, (England)
Abstract:Summary We measured the carotid body volume of rats treated with chronic hypoxia alone and chronic hypoxia together with a single neonatal injection of N-ethyl-N-nitrosourea (10 mg/kg). All the animals so treated showed enlargement of their carotid bodies, but no carotid body chemodectomas occurred.This work was supported by a grant from the North West Cancer Research Fund.
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