| Combined-dynamic mode “dip-pen” nanolithography and physically nanopatterning along single DNA molecules |
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| 作者姓名： | LIBin WANGYing WUHaiping ZHANGYi ZHANGZhixiang ZHOUXingfei LIMinqian HUJun |
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| 作者单位： | [1]ShanghaiInstituteofAppliedPhysics,ChineseAcademyofSciences.Shanghai201800,China [2]ShanghaiJiaotongUniversity,Bio-XScienceResearchCenter.Shanghai200030,China |
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| 摘 要： | Atomic force micriscope (AFM)-based dip-pen nanolithography (DPN) is an emerging approach for constructing nanostructures on material surfaces such as gold, silicon and silicon oxide. Although DPN is a powerful technique, it has not shown its ability of direct-writing and patterning of nanostructures on surfaces of soft materials, for example biomacromolecules. Direct depositing on soft surfaces becomes possible with the introduction of a combined-dynamic mode DPN rather than mostly used contact mode DPN or tapping mode DPN. In this report, the combined dynamic mode DPN is used for direct depositing protein ink on DNA molecules at the nanometer scale.
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| 关 键 词： | 原子力显微镜 浸笔纳米光刻技术 单个DNA分子 纳米结构 材料表面 结合动力模型 纳米图案 |
| 收稿时间： | 2003-09-02 |
| 修稿时间： | 2004-02-06 |
Combined-dynamic mode “dip-pen” nanolithography and physically nanopatterning along single DNA molecules |
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| LIBin WANGYing WUHaiping ZHANGYi ZHANGZhixiang ZHOUXingfei LIMinqian HUJun.Combined-dynamic mode “dip-pen” nanolithography and physically nanopatterning along single DNA molecules[J].Chinese Science Bulletin,2004,49(7):665-667. |
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| Authors: | Li Bin Wang Ying Wu Haiping Zhang Yi Zhang Zhixiang Zhou Xingfei Li Minqian Hu Jun |
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| Institution: | LI Bin1,WANG Ying1,WU Haiping1,ZHANG Yi1,ZHANG Zhixiang1,ZHOU Xingfei1,LI Minqian1 & HU Jun1,2 1.Shanghai Institute of Applied Physics,Chinese Academy of Sciences,Shanghai 201800,China;2.Shanghai Jiaotong University,Bio-X Science Research Center,Shanghai 200030,China |
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| Abstract: | Atomic force micriscope (AFM)-based dip-pen nanolithography (DPN) is an emerging approach for con-structing nanostructures on material surfaces such as gold, silicon and silicon oxide. Although DPN is a powerful tech-nique, it has not shown its ability of direct-writing and pat-terning of nanostructures on surfaces of soft materials, for example biomacromolecules. Direct depositing on soft sur-faces becomes possible with the introduction of a com-bined-dynamic mode DPN rather than mostly used contact mode DPN or tapping mode DPN. In this report, the com-bined dynamic mode DPN is used for direct depositing pro-tein ink on DNA molecules at the nanometer scale. |
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| Keywords: | atomic force microscope (AFM) dip-pen nanolithogra-phy (DPN) single DNA molecules nanostructure |
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