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血清乙型肝炎核心抗原(HBcAg)的研究
引用本文:唐永煌 黄又真. 血清乙型肝炎核心抗原(HBcAg)的研究[J]. 暨南大学学报(自然科学与医学版), 1992, 13(2): 26-31
作者姓名:唐永煌 黄又真
作者单位:暨南大学传染病学教研室,暨南大学传染病学教研室,暨南大学传染病学教研室,暨南大学传染病学教研室,暨南大学附属医院核医学科,暨南大学附属医院核医学科,暨南大学附属医院检验科
摘    要:

关 键 词:乙型肝炎 核心抗原 抗体

A STUDY ON SERUM HEPATITIS B CORE ANTIGEN
Tang Yonghuang Xiao Xichang Xie Xinyong Zhu Shihui. A STUDY ON SERUM HEPATITIS B CORE ANTIGEN[J]. Journal of Jinan University(Natural Science & Medicine Edition), 1992, 13(2): 26-31
Authors:Tang Yonghuang Xiao Xichang Xie Xinyong Zhu Shihui
Affiliation:Tang Yonghuang Xiao Xichang Xie Xinyong Zhu Shihui (Dept.of Infectious Diseases)Huang Youzhen Wang Binyan (Dept.of Nuclear Medicine)Son Aihua (Dept.of Clinical Laboratory)
Abstract:In order to study the relation of HBcAg in serum with five HBV serologic markers (HBsAg,Anti-HBs,HBeAg,Anti-HBe and Anti-HBc),Anti-HBcIgM and various types of hepatitis B,We tested 676 sera for HBcAg with RIA. The result revealed that in 21 models of HBV serologic markers,model 1 (HBsAg,HBeAg and Anti-HBc positive) and model 2 (HBsAg,Anti-HBe and Anti-HBc positive) had higher percentages of HBcAg (91.1% and 86.5%). There was no statistical difference between them (P>0.05).So it was suggested that when HBsAg and Anti-HBc exist,the conversion of E system can not chang the infectivity of serum.There was a good relationship between HBcAg and Anti-HBcIgM,Thus it was likely that Anti-HBcIgM was a marker of HBV replication.Our study also showed that persistent existence of HBV in serum was closely related to the degree of liver disease activity.
Keywords:hepatitis B  markers of HBV  HBcAg  anti-HBcIgM  
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