Modulation of antibody synthesis by an anti-tumour alga |
| |
| Authors: | P J Neveu O Morin M Miègeville B P Le Mevel C Vermeil |
| |
| Institution: | (1) Formation de Recherche Associée no 13 INSERM  Les interactions cellulaires dans le Cancer , UER de Médecine et CRLC Nantes, F-44035 Nantes, (France);(2) Laboratoire de Parasitologie UER de Médicine, F-44035 Nantes Cédex, France |
| |
| Abstract: | Summary An unicellular alga,Chlorella pyrenoidosa, which had been reported to protect C3H mice against sarcoma BP8, is shown, when injected in Freund's incomplete adjuvant, to modulate the antibody synthesis induced by immunization with a hapten-carrier complex.C. pyrenoidosa appeared to be able to initiate an antigenic competition between hapten and carrier determinants of the antigen molecule during antibody synthesis, and thus it could be speculated thatC. pyrenoidosa modulates the immune response at the macrophage level.Acknowledgments. This work was supported by the Secrétariat d'Etat aux Universités and by the DGRST, grant No. 77.71347. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
