Effect of cholesterol oxidation on (Na+, K+) ATPase activity of erythrocyte membranes |
| |
| Authors: | D Seiler W Fiehn |
| |
| Institution: | (1) Medizinische Poliklinik der Universität Heidelberg, Hospitalstrasse 3, D-69 Heidelberg, (German Federal Republic, BRD) |
| |
| Abstract: | Summary By incubation of human erythrocyte ghosts with cholesterol oxidase (EC 1.1.3.6) part of the cholesterol of the membrane is replaced by 4-cholesten-3-one. This alteration in the sterol composition is accompanied by an inhibition of the (Na+, K+) ATPase of the erythrocyte membrane.Acknowledgments. This study was supported by the Deutsche Forschungsgemeinschaft Bonn-Bad Godesberg and the Sonderforschungsbereich 90 of the University of Heidelberg. We thank Mr.J. Schmidt and MissI. Geldmacher for skilful technical assistance. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
