Serum dopamine-beta-hydroxylase activity in a new strain of spontaneously hypertensive rats |
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Authors: | S. Affara L. Denoroy B. Renaud M. Vincent J. Sassard |
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Affiliation: | (1) Départment de Physiologie et Pharmacologie clinique, Faculté de Pharmacie, and Laboratoire de Physiologie, Faculté de Médecine Grange Blanche, 8 avenue Rockefeller, F-69008 Lyon, (France) |
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Abstract: | Summary The serum dopamine- -hydroxylase (DBH) activity is higher in 5-week-old rats of the Lyon Hypertensive strain than in rats of the Lyon Normotensive strain. This difference disappears in older animals when the hypertension is developed, while the DBH activity decreases in the both strains.This work was supported by grants from DGRST (77.7.1930), CNRS (RCP 080.469, ATP A651-3358), INSERM (15.75.38) and the Fondation pour la Recherche Médicale Française. |
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