Sister chromatid exchanges in human lymphocytes exposed to 8-methoxypsoralen and long wave UV radiation prior to incorporation of bromodeoxyuridine |
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| Authors: | D Mourelatos M J W Faed B E Johnson |
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| Institution: | (1) Cytogenetics Laboratory, Department of Pathology and Department of Dermatology, Ninewells Medical School, University of Dundee, DD2 1UB Dundee, (Scotland) |
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| Abstract: | Summary Human lymphocytes exposed to the effects of long wave UV radiation in the presence of 8-methoxypsoralen prior to stimulation by PHA show dose related sister chromatid exchanges after 2 replication cycles in vitro. This has implications for interpreting the repair processes involved and for monitoring DNA damaging agents in vivo. |
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