Regulation of mouse trophoblast giant cell nucleus development in hatched mouse blastocysts by cyclic cytidine 3′,5′-monophosphate (cCMP) |
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| Authors: | P. J. Chan I. Henig D. R. Tredway |
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| Affiliation: | (1) Department of Obstetrics and Gynecology, Oral Roberts University School of Medicine and Hillcrest Fertility Center, 74104 Tulsa, Oklahoma, USA |
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| Abstract: | Summary The dibutyryl analog of cCMP enlarged the nuclei of trophoblast gian cells and promoted blastocyst development. The result suggests that cCMP has a trophic effect on embryonic development, specifically by altering the size of the trophoblast cell nucleus but does not enhance trophoblast cell proliferation processes. |
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| Keywords: | cCMP cyclic nucleotides blastocyst trophoblast mouse |
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