Lesions in the substantia nigra of rats induce thermoregulatory deficit in the cold |
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| Authors: | M. T. Lin A. Chandra Y. M. Chen |
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| Affiliation: | (1) Department of Physiology and Biophysics, National Defense Medical Center, Taipei, (Taiwan) |
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| Abstract: | Summary Rats with either electrolytic or chemical (6-hydroxydopamine) lesions in the substantia nigra displayed decreased metabolism and hypothermia when they were exposed to cold (8 °C Ta), although they showed no deficiency in thermoregulation at both moderate (22 °C) and hot (30 °C) environmental temperatures.This work was supported by grants from the Pjing-Ling Neurological Foundation (Veterans General Hospital, Taipei, Taiwan, China) and the National Science Council (Republic of China). The authors are grateful to Mr C.C. Wei for his generous support. |
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