基于解剖距离的功能脑网络建模方法研究

为了分析解剖距离对静息态功能脑网络建模的影响,在解剖距离的基础上将节点共同邻居引入到功能脑网络的建模中。设计三个模型,分别是基于解剖距离,节点共同邻居个数和解剖距离与节点共同邻居个数。借鉴残差的方法创建最优静息态功能模型网络评价标准。在每种模型网络中选出最优的模型网络。然后将每种模型中的最优网络与真实数据fMRI网络对比选出能够最大程度模拟真实网络的模型网络。结果证明在AAL模板下单独基于解剖距离建立的功能脑网络能最大化的模拟真实的网络。

Research on modeling approach of brain function networkbased on anatomy distance

In order to analyze the effect of anatomy distance on the modeling of resting-state brain function network .The number of common neighbor between nodes be introduced to the modeling of resting-state brain function network . Propose three models and those models of brain function are based on anatomical distance or node similarity or anatomical distance and node similarity . Create the evaluation criteria for select the optimal brain function model network in each class model based on residuals. Select the model that can simulate the real brain function network by comparison with real data fMRI network . Finally , the results show the best model only is based on anatomical distance .