Nerve-growth promoting action of isaxonine in rat |
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| Authors: | A Hugelin Y Legrain M Bondoux-Jahan |
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| Institution: | (1) Laboratoire de Physiologie, CHU Saint-Antoine, Université Pierre et Marie Curie, F-75571 Paris Cédex 12, (France) |
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| Abstract: | Summary After sciatic nerve lesion by freezing, the length of the most rapidly regenerating fibres was significantly increased by i.p. injection of isaxonine (N-isopropyl-amino-2-pyrimidine orthophosphate) in the rat. A dose-effect relationship was demonstrated. Both sensory and motor function returned earlier in treated animals. |
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