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| A Novel Flow Injection Chemiluminescence System for the Determination of Reserpine | |
| 作者姓名： | 庄惠生 王琼娥 魏巧华 吴言林 |
| 作者单位： | College of Environment Science and Engineering，DongHua University，Shanghai 250001，professor，College of Chemistry and Chemical Engineering，DongHua University，Shanghai 250001，Fujian Institute of Research on Structure of Matter，Chinese Academy of Sciences，Fuzhou 350002，Environment Protection Office of Qingpu，Shanghai 201700 |
| 摘 要： | IntroductionReserpine is an effective and safe drug forhypertension. It is a source of rauwolfia alkaloid, whichcan reduce the storage of catecholamine in brain or otherapparatus. Although reserpine determinations have beenwidely reported in pharmaceuticals by fluorimetry1 3],spectrophotometry4] and HPLC5]. These methods to acertain extent suffer from narrow linear ranges andunsatisfactory detection limits. Chemiluminescence ( CL )has been r… |
A Novel Flow Injection Chemiluminescence System for the Determination of Reserpine |
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| ZHUANG Hui-sheng,WANG Qiong-e,WEI Qiao-hua,WU Yan-lin.A Novel Flow Injection Chemiluminescence System for the Determination of Reserpine[J].Journal of Donghua University,2004,21(6). | |
| Authors: | ZHUANG Hui-sheng WANG Qiong-e WEI Qiao-hua WU Yan-lin |
| Institution: | 1. College of Environment Science and Engineering,DongHua University,Shanghai 250001 2. College of Chemistry and Chemical Engineering,DongHua University,Shanghai 250001 3. Fujian Institute of Research on Structure of Matter,Chinese Academy of Sciences,Fuzhou 350002 4. Environment Protection Of fice of Qingpu,Shanghai 201700 |
| Abstract: | A novel flow injection cheminescence (FICL) system for the determination of reserpine is presented in this paper. It is based on the CL reaction of reserpine, IO-4 and H2O2 in H2SO4 medium. The CL intensity was correlated with concentration of reserpine in the range of 1.0×10-6～1.0×10-4g/mL with a detection limit of 1.35×10-7g/ mL. The relative standard deviation is 2.63% for 11 measurements of 2×10-5g/mL reserpine standard solution. The method has been applied to the determination of reserpine in pharmaceutical preparations and the results are in good agreement with that of the standard method. |
| Keywords: | Reserpine Flow Injection Chemiluminescence Determination |
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