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| 福多司坦合成工艺研究 | |
| 引用本文： | 徐桂清,毛润泽,孙青斌,韩会娟,郝二军,王慧芳,李伟.福多司坦合成工艺研究[J].河南师范大学学报(自然科学版),2011,39(3):103-104. |
| 作者姓名： | 徐桂清 毛润泽 孙青斌 韩会娟 郝二军 王慧芳 李伟 |
| 作者单位： | 1. 河南师范大学,化学与环境科学学院,河南新乡453007 2. 新乡市环保局,河南新乡,453003 3. 河南科技学院化学化工学院,河南新乡,453000 |
| 摘 要： | 以L-半胱氨酸盐酸盐为起始原料,在氧化-还原体系催化下与烯丙醇发生反应,制得祛痰药福多司坦,总收率达到91%.目标化合物的结构经1H-NMR,IR确证.与文献相比,该法操作简单,收率高,适合工业化生产. |
| 关 键 词： | 福多司坦 L-半胱氨酸 烯丙醇 合成 |
Synthesis of Fudosteine |
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| XU Gui-qing,MAO Run-ze,SUN Qing-bin,HAN Hui-juan,HAO Er-Jun,WANG Hui-Fang,LI Wei.Synthesis of Fudosteine[J].Journal of Henan Normal University(Natural Science),2011,39(3):103-104. | |
| Authors: | XU Gui-qing MAO Run-ze SUN Qing-bin HAN Hui-juan HAO Er-Jun WANG Hui-Fang LI Wei |
| Institution: | 1(1.College of Chemistry and Environmental Science,Henan Normal University,Xinxiang 453007,China; 2.Xinxiang Environmental Protection Agency,Xinxiang 453003,China;3.School of Chemistry and Chemical Engineering,Henan Institute of Science and Technology,Xinxiang 453000,China) |
| Abstract: | Expectorant fudosteine is synthesized from L-cysteine hydrochloride using oxidation-reduction system catalyst with an overall yield of about 91%.The structure of the target product is characterized by 1H-NMR and IR.The method has the advantages of simple and hihger yields,which is suitable for industrialization. |
| Keywords: | fudosteine L-cysteine allyl alcohol synthesis |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |