首页 | 本学科首页   官方微博 | 高级检索  
     


Stable isotopes of lithium: dissimilar biochemical and behavioral effects
Authors:K. Lieberman  G. J. Alexander  J. A. Sechzer
Affiliation:(1) Laboratory of Psychopharmacology, Catholic Medical Center of Brooklyn and Queens, 88-25 153rd Street, 11432 Jamaica, New York, USA;(2) Dept of Psychiatry, Tufts University School of Medicine, Boston, Massachusetts, USA;(3) College of Physicians and Surgeons, New York State Psychiatric Institute and Columbia University, New York, New York, USA;(4) Bourne Behavioral Research Laboratory, Dept of Psychiatry, New York Hospital-Cornell Medical Center, White Plains, New York, USA
Abstract:Summary Lithium, which is used routinely in the treatment of mania, is composed of two stable isotopes, lithium-7 (92.58%) and lithium-6 (7.42%). Usually there is minimal physiological or biochemical differentiation between isotopes of an element, but lithium is an exception. Data derived from a variety of biochemical and behavioral experiments are reviewed to support this idea. Additionally, the clinical implications of this work are presented.
Keywords:Lithium  isotopes  lithium-6  lithium-7  mania
本文献已被 SpringerLink 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号