Prevention of enteral radiocesium absorption by hexacyanoferrates(II) in piglets |
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| Authors: | P. Nielsen R. Fischer H. C. Heinrich A. A. Pfau |
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| Affiliation: | (1) Medizinische Biochemie, Institut für Physiologische Chemie, Universitätskrankenhaus Eppendorf, Martinistraße 52, D-2000 Hamburg 20, Federal Republic of Germany;(2) Radiobiologie, Institut für Tierzucht und Tierverhalten, Bundesforschungsanstalt für Landwirtschaft, Mariensee, D-3057 Neustadt a. Rbg., Federal Republic of Germany |
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| Abstract: | Summary The efficacy of different hexacyanoferrates(II) in preventing the enteral absorption of134Cs was studied in piglets. As compared to the controls, oral application of134Cs together with KFe[Fe(CN)6], NH4Fe[Fe(CN)6], or Fe4[Fe(CN)6]3 resulted in a strong reduction of the134Cs-uptake by more than 97%. The decrease in enteral absorption depends on the dose of administered hexacyanoferrate(II), whereas differences between the compounds under study were small. The biological half-life of134Cs in non-hexacyanoferrate(II) treated piglets was 21.6±3.3 days (mean±SD). |
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| Keywords: | Hexacyanoferrate(II) 134Cs cesium absorption biological half-life piglet |
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