Effect of pancreatic secretions upon ileal disaccharidase activities of neonatal miniature pigs |
| |
Authors: | D R Tivey R J Shulman |
| |
Institution: | AFRC Institute of Animal Physiology & Genetics Research, Babraham, Cambridge, England. |
| |
Abstract: | Mechanisms by which pancreatic secretions influence disaccharidase activities in the distal small intestine have been investigated in 1-week-old miniature pigs. Using a combination of biochemical, cytochemical and morphological techniques it has been found that the decrease in lactase specific activity is due solely to a reduction in villus surface area. By contrast, the increased sucrase-isomaltase activities, which occur despite the reduction in villus surface area, are due entirely to increased enzyme expression during enterocyte differentiation. |
| |
Keywords: | |
|
|