| 家蚕基因组P450基因家族的分析 |
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| 引用本文： | 周权,王宝玉.家蚕基因组P450基因家族的分析[J].皖西学院学报,2010,26(5):74-76. |
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| 作者姓名： | 周权 王宝玉 |
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| 作者单位： | [1]安徽农业大学研究生学院,安徽合肥230036 [2]阜阳师范学院附属中学,安徽阜阳236041 |
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| 摘 要： | 利用家蚕基因组mRNA和氨基酸数据库对P450基因进行搜索．结果显示：在家蚕基因组中发现77个P450基因．分别归于18个P450家族和26个亚家族，其中有9个多基因家族。3个基因家族的成员超过10个，CYP4有20个成员。是一个典型的多基因家族。对P450基因进行正选择、基因转换和基序分析。结果表明：1个组（包含3个P450s基因）中检测出了显著的正选择替换位点，在这1个组中．转换事件的次数为3次。
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| 关 键 词： | 家蚕 细胞色素P450 正选择 基因转换 |
A Genome-wide Analysis of P450 Gene Family in Silkworm |
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| ZHOU Quan,WANG Bao-yu.A Genome-wide Analysis of P450 Gene Family in Silkworm[J].Journal of Wanxi University,2010,26(5):74-76. |
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| Authors: | ZHOU Quan WANG Bao-yu |
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| Institution: | 1. Graduate School,Anhui Agricultural University, Hefei 230036, China; 2. The Affiliated Middle School ,Fuyang Teachers College ,Fuyang 230062,China) |
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| Abstract: | A genome-wide analysis of P450 genes were performed in silkworm genome based on their mRNA and amino acid data.77 P450 genes,assigned into 18 gene families and 26 subfamilies,were identified,it contains 9 multi--gene family, 3 gene family has more than 10 members in it. CYP4 have 20 members,is a typical multi-gene family. P450 genes of silkworm positive selection,gene conversion and base sequence analysis,results showed that： A group （including three P450s genes） deteeted significant site is to choose the replacement,in this one group, the number of conversion events 3 times. |
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| Keywords: | silkworm cytochrome P450 positive selection gene conversion |
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