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Circadian fluctuation of susceptibility to haloperidol under constant conditions
Authors:H Nagayama  A Takagi  R Takahashi
Institution:(1) Department of Neuropsychiatry, Medical College of Oita, 879-56 Oita, (Japan);(2) Takagi Mental Hospital, 855 Shimabara, (Japan);(3) Department of Neuropsychiatry, Tokyo Medical and Dental University, School of Medicine, 113 Tokyo, (Japan)
Abstract:Summary An endogenous circadian rhythm of the sedative and antiapomorphine effects of haloperidol was observed under constant conditions for 7 days as well as under an entrained light-dark cycle.
Keywords:Haloperidol  circadian rhythm  sedation  antiapomorphine effect  constant condition
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