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The absence of an inhibitory effect of metyrapone (2-methyl-1,2-di (3-pyridyl) propan-1-one) on hepatic microsomal hydroxylation in scurvy
Authors:A. M. Fielding  R. E. Hughes
Affiliation:(1) Department of Applied Biology, University of Wales Institute of Science and Technology, Cardiff, (Wales, G.B.)
Abstract:Summary Microsomes from livers of scorbutic guineapigs showed a reduced rate of acetanilide hydroxylation. The response of lsquoscorbuticrsquo liver microsomes to the inhibitor Metyrapone (2-methyl-1,2 di (3-pyridyl)propan-1-one) was different from that of liver microsomes from non-scorbutic guinea-pigs.
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