| Preparation and characterization of chitosan/nano-hydroxyapatite composite used as bone substitute materials |
| |
| 作者姓名： | 张利 Li Yubao Zhou Gang Wu Lan Mu Yuanhua Yang Zheng |
| |
| 作者单位： | Research Center for Nano-Biomaterials, Analytical ＆ Testing Center, Siehuan University, Chengdu 610064, P.R. China |
| |
| 基金项目： | 国家重点基础研究发展计划(973计划) |
| |
| 摘 要： | Chitosan/nano-hydroxyapatite composites with different weight ratios were prepared through a co-precipitation method using Ca（OH）2, H3PO4 and chitosan as starting materials. The properties of these composites were characterized by means of TEM, IR, XRD, TGA, burn-out tests and universal matertial testing machine. The results showed that the HA synthesized here was poorly crystalline carbonated nanometer crystals and dispersed uniformly in chitosan phase and there was no phase-separation between the two phases. The addition of n-HA resulted in a decrease of decomposing temperature of chitosan. Because of the interactions between chitosan and n-HA, the mechanical properties of these composites were improved, and the maximum value of the compressive strength was measured to be about 120MPa corresponding to the chitosan/n-HA composite with a weight ratio of 30/70.
|
| 关 键 词： | 壳聚糖 纳米羟基磷灰石 复合材料 骨骼替代材料 制备 表征 |
| 收稿时间： | 2005-08-30 |
Preparation and characterization of chitosan/nano-hydroxyapatite composite used as bone substitute materials |
| |
| Zhang Li,Li Yubao,Zhou Gang,Wu Lan,Mu Yuanhua,Yang Zheng.Preparation and characterization of chitosan/nano-hydroxyapatite composite used as bone substitute materials[J].High Technology Letters,2007,13(1):31-35. |
| |
| Authors: | Zhang Li Li Yubao Zhou Gang Wu Lan Mu Yuanhua Yang Zheng |
| |
| Abstract: | Chitosan/nano-hydroxyapatite composites with different weight ratios were prepared through a co-precipitation method using Ca(OH)2, H3PO4 and chitosan as starting materials. The properties of these composites were characterized by means of TEM, IR, XRD, TGA, bum-out tests and universal matertial testing machine. The results showed that the HA synthesized here was poorly crystalline carbonated nanometer crystals and dispersed uniformly in chitosan phase and there was no phase-separation between the two phases. The addition of n-HA resulted in a decrease of decomposing temperature of chitosan. Because of the interactions between chitosan and n-HA, the mechanical properties of these composites were improved, and the maximum value of the compressive strength was measured to be about 120MPa corresponding to the chitosan/n-HA composite with a weight ratio of 30/70. |
| |
| Keywords: | chitosan nano-hydroxyapatite composite co-precipitation |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
