短瓣兰的化学成分研究

对短瓣兰根的丙酮提取物进行化学成分研究.利用各种色谱技术进行分离纯化,根据理化性质、波谱特征鉴定结构.分离并鉴定了16个菲类化合物,分别为2,2′-dimethoxy-9,9′,10,10′-dihydro-1,1′-biphenanthrene]-4,4′,7,7′-tetrol(1), flavanthrin(2),Blestriarene B(3),Blestriarene C(4),2,2′-dihydroxy-4,7,4′,7′-tetramethoxy-1,1′-biphenanthrene(5),2,7,2-trihydroxy-4,4,7-trimethoxy -1,1-biphenanthrene(6),lusianthridin(7),orchinol(8),coelonin(9),6-methoxycoelonin(10),dehydroorchinol(11),2-hydroxy-4,7-dimethoxyphenanthrene(12),2-methoxymoscatin(13),4,7-dihydroxy -1-(4-hydroxybenzyl) -2-methoxy-9,10-dihydrophenanthrene(14),2,7-dihydroxy-1,3-bi(p-hydroxybenzyl) -4-methoxy-9,10-dihydrophenanthrene(15),2,7-dihydroxy-1,6-bi(p-hydroxybenzyl) -4-methoxy-9,10-dihydrophenanthrene(16).化合物1～16均为首次从该植物中分离得到,并首次使用2D-NMR对化合物1的数据进行了准确归属.

Studies on the chemical constituents of Monomeria barbata

The chemical constituents of Monomeria barbata were studied and 16 compounds were isolated by the method of silica gel column chromatography.The structures of these compounds were elucidated by spectral analyses and chemical properties.Their structures were identified as 2,2′-dimethoxy-9,9′,10,10′-dihydro-1,1′-biphenanthrene]- 4,4′,7,7′-tetrol (1),flavanthrin (4,4′-dimethoxy-9,9′,10,10′-dihydro- 1,1′- biphenanthrene]- 2,2′,7,7′- tetrol) (2) ,Blestriarene B (3),Blestriarene C (4),2,2′-dihydroxy-4,7,4′,7′-tetramethoxy-1,1′-biphenanthrene (5),2,7,2-trihydroxy-4,4,7-trimethoxy -1,1-biphenanthrene (6),lusianthridin (7),orchinol (8),coelonin (9),6-methoxycoelonin (10),dehydroorchinol (11),2-hydroxy-4,7-dimethoxyphenanthrene (12),2-methoxymoscatin (13),4,7-dihydroxy -1-(4- hydroxybenzyl) -2-methoxy-9,10-dihydrophenanthrene (14),2,7-dihydroxy-1,3-bi (p-hydroxybenzyl) -4-methoxy-9,10-dihydrophenanthrene (15),2,7-dihydroxy-1,6-bi (p-hydroxybenzyl) -4-methoxy- 9,10-dihydrophenanthrene (16).All these compounds are identified and isolated from this plant for the first time.