Synthesis and antitumour activity of new daunorubicin and adriamycin analogues |
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| Authors: | F. Arcamone L. Bernardi B. Patelli P. Giardino A. Di Marco A. M. Casazza C. Soranzo G. Pratesi |
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| Affiliation: | (1) Farmitalia, Ricerca Chimica, via dei Gracchi 35, I-20146 Milano, (Italy);(2) Istituto Nazionale per lo Studio e la Cura dei Tumori, via Venezia 1, I-20133 Milano, (Italy) |
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| Abstract: | Summary A new synthetic procedure for the preparation of daunorubicin and adriamycin analogues bearing different substituents on ring D, has been developed. The new compounds display outstanding efficacy against experimental tumours of mice. |
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