Papaverine enhances the negative inotropic effect of acetylcholine in rat auricles |
| |
Authors: | H. Nawrath |
| |
Affiliation: | (1) Department of Pharmacology, University of Mainz, Obere Zahlbacher Str. 67, D-6500 Mainz, (Federal Republic of Germany) |
| |
Abstract: | Summary The negative inotropic effect of acetylcholine in rat left auricles is enhanced in the presence of the phosphodiesterase inhibitor papaverine. This result favours the idea of a cyclic GMP-mediated action of acetylcholine in the heart.I thank Lydia Paragnik for help. This research was supported by a grant from the Deutsche Forschungsgemeinschaft. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|