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吉祥草根茎化学成分研究
引用本文:王倩,郭志勇,邹坤. 吉祥草根茎化学成分研究[J]. 三峡大学学报(自然科学版), 2012, 34(1): 82-84
作者姓名:王倩  郭志勇  邹坤
作者单位:三峡大学化学与生命科学学院天然产物研究与利用湖北省重点实验室,湖北宜昌,443002
基金项目:国家自然科学基金面上项目(30870254,31070313)
摘    要:目的:研究吉祥草根茎中化学成分,寻找抗肿瘤活性物质.方法:运用反相常压柱色谱和制备高效液相对其化学成分进行分离,通过理化性质和波谱分析方法鉴定结构.结果:从吉祥草根茎的乙醇提取物中分离得到3个甾体化合物及2个黄酮,经鉴定其结构分别为nicotianoside B(1),胡萝卜苷(2),β-ecdysone(2β,3β,14α,20R,22R,25-hexahydroxy-5β-cholest-7-en-6-one)(3),槲皮素(4),芦丁(5).结论:化合物3为首次从该属植物中分离获得.

关 键 词:吉祥草  抗肿瘤活性  皂苷  黄酮

Studies of Chemical Constituents from Rhizome of Reineckia Carnea
Wang Qian , Guo Zhiyong , Zou Kun. Studies of Chemical Constituents from Rhizome of Reineckia Carnea[J]. Journal of China Three Gorges University(Natural Sciences), 2012, 34(1): 82-84
Authors:Wang Qian    Guo Zhiyong    Zou Kun
Affiliation:Wang Qian Guo Zhiyong Zou Kun(Hubei Key Laboratory of Natural Products Research & Development,College of Chemistry & Life Science,China Three Gorges Univ.,Yichang 443002,China)
Abstract:To study the chemical constituents from rhizome of Reineckia carnea and search for bioactive compounds with potential antitumor activity.The compounds were isolated by RP-C18 column chromatography and preparative HPLC.The structures of the compounds were identified on the basis of the spectroscopic analysis and chemical evidences.Three steroids(1-3) and two flavonoids(4-5) were obtained from the Reineckia carnea rhizomes.Their structures were determined as Nicotianoside B(1),Daucosterol(2),β-ecdysone(2β,3β,14α,20R,22R,25-hexahydroxy-5β-cholest-7-en-6-one)(3),Quercetin(4) and Rutin(5),respectively.Compound 3 was isolated from the Reineckia carnea for the first time.
Keywords:Reineckia carnea  antitumor activity  steroids  flavonoids
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