| 不同市售野菊花药材的RP—HPLC指纹图谱 |
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| 引用本文： | 毕跃峰,符玲,王蒲菊,孙孝莉,刘晓庆. 不同市售野菊花药材的RP—HPLC指纹图谱[J]. 郑州大学学报(自然科学版), 2010, 0(4): 92-94 |
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| 作者姓名： | 毕跃峰 符玲 王蒲菊 孙孝莉 刘晓庆 |
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| 作者单位： | 郑州大学药学院新药研发中心,河南郑州450001 |
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| 基金项目： | 基金项目：国家自然科学基金资助项目,编号30973872. |
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| 摘 要： | 采用反相高效液相色谱（RP—HPLC）法，以甲醇和醋酸（体积分数4％）为流动相梯度洗脱，建立了野菊花药材的指纹图谱，并标定出25个共有峰，指认出9个特征峰．测定了12批不同市售野菊花药材的相似度．所建立的野菊花药材RP—HPLC色谱指纹图谱重复性好，专属性强，可用于野菊花药材的质量评价．
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| 关 键 词： | 野菊花 RP—HPLC 指纹图谱 |
RP-HPLC Fingerprint for Flos Chrysanthemi indici from Different Sources |
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| BI Yue-feng,FU Ling,WANG New Drugs Research and Development Zhengzhou University,Pu-ju,SUN Xiao-li,LIU Xiao-qing. RP-HPLC Fingerprint for Flos Chrysanthemi indici from Different Sources[J]. Journal of Zhengzhou University (Natural Science), 2010, 0(4): 92-94 |
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| Authors: | BI Yue-feng FU Ling WANG New Drugs Research Development Zhengzhou University Pu-ju SUN Xiao-li LIU Xiao-qing |
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| Affiliation: | Center, School of Pharmaceutical Sciences, Zhengzhou 450001, China) |
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| Abstract: | RP-HPLC fingerprint methods for Flos Chrysanthemi Indici is established. The RPHPLC system consists of a mixture of methanol and 4% acetic acid with gradient elution. 25 same characteristic peaks of Flos Chrysanthemi indici are established and 9 characteristic peaks are recognized. Based on the chromatographic fingerprints, the similarity of Flos Chrysanthemi indici from 12 different sources is analyzed. The results show that the chromatographic finger- print for Flos Chrysantherni indici is repeatable, feasible and can be used to estimate the quality of Flos Chrysanthemi indici. |
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| Keywords: | Flos Chrysanthemi indici RP-HPLC fingerprint |
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