Intranuclear crystalloids in arcuate nucleus neurons after clomiphene citrate administration |
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| Authors: | M Alvarez-Uria G Gonzalez A Menendez |
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| Institution: | (1) Dept of Microscopical Morphology, Julian Claveria s/n, E-33006 Oviedo, (Spain) |
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| Abstract: | Summary The action of high doses of clomiphene citrate on the nuclei of hypothalamic arcuate neurons of male cats has been studied. Clomiphene produces an accumulation of typical crystalloid material in the nuclei. After administration of a protein-synthesis inhibitor, no such material was observed in clomiphene-treated animals.These ultrastructural features could possibly be due to a more intense protein synthesis in the hypothalamic arcuate neurons. |
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| Keywords: | Hypothalamus arcuate nucleus intranuclear inclusions clomiphene male cat |
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