| 心肌肥厚大鼠血管膜周脂肪组织对血管舒缩功能的影响 |
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| 引用本文： | 胡存华,梁生林.心肌肥厚大鼠血管膜周脂肪组织对血管舒缩功能的影响[J].井冈山学院学报,2006(10). |
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| 作者姓名： | 胡存华 梁生林 |
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| 作者单位： | 井冈山学院医学院药理教研室 江西吉安343000 |
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| 摘 要： | 目的:观察正常大鼠及部分结扎腹主动脉致心肌肥厚大鼠的血管膜周脂肪组织对血管舒缩功能的影响。方法:手术部分结扎腹主动脉致心肌肥厚模型,采用血管张力记录法,观察正常大鼠及模型大鼠血管膜周脂肪组织对血管舒缩功能的影响。结果:对于正常大鼠,血管膜周脂肪组织可显著降低血管对苯肾上腺素的反应性;对于模型鼠,血管膜周脂肪组织可显著升高血管对苯肾上腺素的反应性。结论:血管膜周脂肪组织对于血管的舒缩功能有重要的调节作用。
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| 关 键 词： | 血管膜周脂肪 心肌肥厚 血管反应性 |
The effect of perivascular adipose tissue on vascular responsiveness in myocardial hypertrophy rats |
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| HU Cun-Hua,LIANG Sheng-Lin.The effect of perivascular adipose tissue on vascular responsiveness in myocardial hypertrophy rats[J].Journal of Jinggangshan University,2006(10). |
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| Authors: | HU Cun-Hua LIANG Sheng-Lin |
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| Abstract: | Objective: To observe the effect of perivascular adipose tissue on vascular responsiveness in normal and myocardial hypertrophy rats.Methods: The model of myocardial hypertrophy was made by abdominal aorta ligation,then the vascular tension was observed to response the effect of perivascular adipose tissue on vascular responsiveness in normal and myocardial hypertrophy rats.Results: In normal rats,perivascular adipose tissue can decrease the vascular responsiveness to the phenylephrine,while increasing effect was presented in myocardial hypertrophy rats.Conclusion: perivascular adipose tissue play an important role on vascular responsiveness. |
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| Keywords: | Perivascular adipose Tissue Myocardial Hypertrophy Vascular Responsiveness |
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