| A symmetry-related sequence-structure relation of proteins |
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| 作者姓名： | XURuizhen LIMingfen CHENHanlin HUANGYanzhao XIAOYi |
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| 作者单位： | BiomolecularPhysicsandModelingGroup,DepartmentofPhysics,HuazhongUniversityofScienceandTechnology,Wuhan430074,China |
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| 摘 要： | Proteins have regular tertiary structures but irregular amino acid sequences. This made it very difficult to decode the structural information in the protein sequences. Here we demonstrate that many small α protein domains have hidden sequence symmetries characteristic of their pseudo-symmetric tertiary structures. We also present a modified method of recurrent plot to reveal this kind of the hidden sequence symmetry. The results may enable us to understand part of the relations between protein sequences and their tertiary structures.
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| 关 键 词： | 序列结构 蛋白质 氨基酸 编码 对称结构 |
| 收稿时间： | 27 November 2004 |
A symmetry-related sequence-structure relation of proteins |
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| XURuizhen LIMingfen CHENHanlin HUANGYanzhao XIAOYi.A symmetry-related sequence-structure relation of proteins[J].Chinese Science Bulletin,2005,50(6):536-538. |
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| Authors: | Ruizhen Xu Mingfen Li Hanlin Chen Yanzhao Huang Yi Xiao |
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| Institution: | (1) Biomolecular Physics and Modeling Group, Department of Physics, Huazhong University of Science and Technology, 430074 Wuhan, China |
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| Abstract: | Proteins have regular tertiary structures but irregular amino acid sequences. This made it very difficult to decode the structural
information in the protein sequences. Here we demonstrate that many small α protein domains have hidden sequence symmetries
characteristic of their pseudo-symmetric tertiary structures. We also present a modified method of recurrent plot to reveal
this kind of the hidden sequence symmetry. The results may enable us to understand part of the relations between protein sequences
and their tertiary structures. |
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| Keywords: | protein symmetry sequence-structure relation recur- rence quantification analysis |
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