| 喹诺酮化合物环丙化反应的研究 |
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| 引用本文： | 汪敦佳,董镜华,邹光中.喹诺酮化合物环丙化反应的研究[J].湖北师范学院学报(自然科学版),1999(1). |
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| 作者姓名： | 汪敦佳 董镜华 邹光中 |
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| 作者单位： | 湖北师范学院化学系!黄石435002 |
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| 摘 要： | 首次以溴代环丙烷为烷化剂，以季铵盐为相转移催化剂，无机碱为缚酸剂，在非质子极性溶剂介质中对喹诺酮化合物的环丙化反应进行了研究，并取得了较好的效果，环丙化收率可达73．1％。
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| 关 键 词： | 环丙化反应 相转移催化剂 喹诺酮化合物 |
RESEARCH ON THE CYCLYPROPYLATIONOF QUINOLONE COMPOUND |
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| Wang Dun ,jia Dong, Jinghua Zou, Guangzhong.RESEARCH ON THE CYCLYPROPYLATIONOF QUINOLONE COMPOUND[J].Journal of Hubei Normal University(Natural Science),1999(1). |
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| Authors: | Wang Dun jia Dong Jinghua Zou Guangzhong |
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| Abstract: | The cyclopropylation of quinolone compound was studied via phase transfer catalysis in the rnedium ofthe aprotic polar solvent,in which bromocyclopropane was used as a alkylating agent,inorganic base as a condensingagent and quarternary ammonium salt as a phase transfer catalyst,and the better results were obtained. The yleld of cyclopropylation was 73. 1 %. |
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| Keywords: | cyclopropylation phase transfer catalyst quinolone compound |
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