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Do prostaglandins mediate the somatostatin preventive effect on gastric lesion?
Authors:S F Aliño
Institution:(1) Department of Histology, Faculty of Medicine, University of Pais Vasco, Lejona, Vizcaya, (Spain)
Abstract:Summary The inhibition of endogenous prostaglandin synthesis by indomethacin treatment blocks the somatostatin preventive effect on the gastric lesions induced in a stress model and has no preventive effect on an intragastric distension model.
Keywords:Rat  prostaglandins  gastric lesion  intragastric distension model  stress model  indomethacin  somatostatin preventive effect
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