Intramitochondrial inclusions in maturing and senescent muscle cells of rat myocardium |
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Authors: | J Cano A Machado |
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Institution: | (1) Departamento de Morfologia, Facultad de Medicina, Universidad Autonoma, 34 Madrid, (Spain);(2) Departamento de Bioquimica, Facultad de Farmacia, Sevilla, (Spain) |
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Abstract: | Summary Intramitochondrial myelin-like structures were found in ventricular myocardial cells of the rat heart. These inclusions were found in both the first 2 postnatal weeks and in senescent stages. The origin of such myelin-like structures could be related to an age-dependent metabolic change, specifically to an inability to oxidize long-chain fatty acids described in both periods.Acknowledgment. This work was supported by grant No. 801/82 of CAICYT. |
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