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Factors influencing the distribution of 99m-technetium methylene diphosphonate in bone and soft tissues
Authors:Ralph A. A. Khan
Affiliation:(1) Radiotherapy Department, Supervoltage Unit, Hammersmith Hospital, Ducane Road, W12 OHS London, (England)
Abstract:Summary The influences of dilution, storage and pH on the distribution of 99m-technetium methylene diphosphonate (99m-Tc-MDP) in bone and various soft tissues have been investigated in the rat. The results show a marked departure from normality when large dilution factors and very acidic or basic preparations are used.
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